IL-1 alpha, murine recombinant

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SKU:
4126-50
€185
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Description

IL-1 alpha, murine recombinant is available at Gentaur for Next week delivery.

Activates TNF-α and plays a critical role in immune response regulation

Biomolecule/Target: IL-1 alpha

Alternates names: Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)

Synonyms: Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)

Background Information: Recombinant mouse Interleukin-1 alpha (IL-1α) produced in E. coli is a non-glycosylated polypeptide chain containing 156 amino acids and has a molecular weight of 18 kDa. Murine IL-1α is a potent immuno-modulator that mediates a wide range of immune and inflammatory responses.

Reconstitution Instructions: Reconstitute in H₂O to a concentration of not less than 100 µg/ml. which can then be diluted into other aqueous solutions.

NCBI Gene Symbol: IL1A

Gene ID: 16175

NCBI Accession: Q3U0Y6

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Additional Information

Size:
50 μg
Adwords:
Yes
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Mouse
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of murine D10S cells was found to be < 0.01ng/ml, corresponding to a specific activity of 1 x 108 IU/mg.
Results:
< 0.01ng/ml,
Molecular Weight:
18.0 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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