Description
Human Recombinant TNF-beta/LTA is available at Gentaur for Next week delivery.
Mediates a large variety of inflammatory, immunostimulatory, and antiviral responses
Biomolecule/Target:
Alternates names: Lymphotoxin alpha, LT, TNFB, TNFSF1.
Synonyms: Human Recombinant TNF-beta/LTA
Background Information: TNF-beta, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. It is highly inducible, secreted, and exists as homotrimeric molecule. It forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. It mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. It is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis.
Reconstitution Instructions: N/A
NCBI Gene Symbol: LTA
Gene ID: 4049
NCBI Accession: P01374
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. Coli |
Purity by SDS-PAGE: |
≥90% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Measured in a cytotoxicity assay using L929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is <0.3 ng/ml. |
Results: |
<0.3 ng/ml |
Molecular Weight: |
20.9 kDa (192 aa, 35-205 aa + His-Tag) |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
0.5 mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |