Human Recombinant TNF-beta/LTA

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SKU:
6376-50
€185
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Description

Human Recombinant TNF-beta/LTA is available at Gentaur for Next week delivery.

Mediates a large variety of inflammatory, immunostimulatory, and antiviral responses

Biomolecule/Target:

Alternates names: Lymphotoxin alpha, LT, TNFB, TNFSF1.

Synonyms: Human Recombinant TNF-beta/LTA

Background Information: TNF-beta, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. It is highly inducible, secreted, and exists as homotrimeric molecule. It forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. It mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. It is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis.

Reconstitution Instructions: N/A

NCBI Gene Symbol: LTA

Gene ID: 4049

NCBI Accession: P01374

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. Coli
Purity by SDS-PAGE:
≥90%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
N/A
Biological activity:
Measured in a cytotoxicity assay using L929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is <0.3 ng/ml.
Results:
<0.3 ng/ml
Molecular Weight:
20.9 kDa (192 aa, 35-205 aa + His-Tag)
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
0.5 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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