Human Recombinant SHP-1

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SKU:
6302-100
€185
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Description

Human Recombinant SHP-1 is available at Gentaur for Next week delivery.

A signaling molecule that regulates a variety of cellular processes

Biomolecule/Target:

Alternates names: Protein tyrosine phosphatase, non-receptor type 6 isoform 1, PTPN6, HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1L, SHP1.

Synonyms: Human Recombinant SHP-1

Background Information: The protein coding region of the catalytic domain of SHP-1 (amino acids 243-541) was cloned into an E. coli expression vector. The catalytic domain of SHP-1 was overexpressed as insoluble protein aggregates (inclusion bodies). The recombinant SHP-1 protein was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer. Additional amino acid (Met) is attached at N-terminus.

Reconstitution Instructions: N/A

NCBI Gene Symbol: PTPN6

Gene ID: 5777

NCBI Accession: P29350

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Additional Information

Size:
100 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
< 1.0 EU per 1 μg of protein (determined by LAL method)
Activity (Specifications/test method):
N/A
Biological activity:
>5,000 units/mg of SHP-1.
Results:
N/A
Molecular Weight:
34.3 kDa (300 aa)
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
1 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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