Human Recombinant Neuron-Specific Enolase (NSE)

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SKU:
6362-100
€185
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Description

Human Recombinant Neuron-Specific Enolase (NSE) is available at Gentaur for Next week delivery.

A useful tumor marker for lung cancer patients

Biomolecule/Target:

Alternates names: Enolase 2 (gamma, neuronal), ENO2.

Synonyms: Human Recombinant Neuron-Specific Enolase (NSE)

Background Information: Neuron-specific enolase (NSE) is a glycolytic isoenzyme which is located in central and peripheral neurons and neuroendocrine cells. This enzyme is released into the CSF when neural tissue is injured. Neoplasms derived from neural or neuroendocrine tissue may release NSE into the blood. NSE is a useful substance that has been detected in patients with certain tumors, namely - neuroblastoma, small cell lung cancer, medullary thyroid cancer, carcinoid tumors, pancreatic endocrine tumors, and melanoma. NSE shows neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons and binds in a calcium-dependent manner to cultured neocortical neurons promoting cell survival.

Reconstitution Instructions: N/A

NCBI Gene Symbol: ENO2

Gene ID: 2026

NCBI Accession: P09104

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Additional Information

Size:
100 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. Coli
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
<1.0 EU per 1 μg of protein (determined by LAL method).
Activity (Specifications/test method):
N/A
Biological activity:
Specific activity: >8 units/ml.
Results:
>8 units/ml
Molecular Weight:
47 kDa (434 aa, 1-434 aa)
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
1 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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