Description
Human CellExp™ TNFRSF4/OX40 /CD134, human recombinant is available at Gentaur for Next week delivery.
Plays an important role in CD4+ and CD8+ T-cells and B-cells response.
Biomolecule/Target: TNFRSF4/OX40 /CD134
Alternates names: TNFRSF4, OX40, CD134, OX40L receptor, ACT35, TXGP1L
Synonyms: TNFRSF4, OX40, CD134, OX40L receptor, ACT35, TXGP1L
Background Information: Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) is also known as ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, CD antigen CD134, OX40. OX40 / TNFRSF4 contains four TNFR-Cys repeats. TNFRSF4 is receptor for TNFSF4 / OX40L / GP34 and can interacts with TRAF2, TRAF3 and TRAF5.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
NCBI Gene Symbol: TNFRSF4
Gene ID: 7293
NCBI Accession: P43489
Additional Information
Size: |
10 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK293 cells |
Purity by SDS-PAGE: |
≥92% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
<1 EU/μg by LAL method |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Measured by its binding ability in a functional ELISA. Immobilized rh TNFRSF4 / OX40 / CD134 at 2 μg/ml (100 μl/well) can bind human TNFSF4 Fc Chimera. The EC50 of human TNFSF4 Fc Chimera is 30 ng/mL. |
Results: |
Measured by its binding ability in a functional ELISA. Immobilized rh TNFRSF4 / OX40 / CD134 at 2 μg/ml (100 μl/well) can bind human TNFSF4 Fc Chimera. The EC50 of human TNFSF4 Fc Chimera is 30 ng/mL. |
Molecular Weight: |
This protein is fused with 6× his tag at the C-terminus, and has a calculated MW of 21 kDa. The predicted N-terminus is Leu 29. DTT-reduced Protein migrates as 35-48 kDa in SDS-PAGE due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |