Description
Human CellExp™ Siglec-6 / CD327 Protein, Fc Tag is available at Gentaur for Next week delivery.
A cell surface protein primarily on the surface of immune cells that mediates sialic-acid dependent binding to cells.
Biomolecule/Target: Siglec-6 / CD327 Fc Tag
Alternates names: SIGLEC6, CD327, CD33L, CD33L1, OBBP1, OB-BP1, CDw327
Synonyms: SIGLEC6, CD327, CD33L, CD33L1, OBBP1, OB-BP1, CDw327
Background Information: Sialic acid-binding Ig-like lectin 6 (SIGLEC6) is also known as CD antigen CD327, CD33 antigen-like 1 (CD33L or CD33L1), Obesity-binding protein 1 (OB-BP1). SIGLEC6 belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family, which contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIGLEC6 mediates sialic-acid dependent binding to cells. SIGLEC6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Reconstitution Instructions: . Reconstitute in sterile deionized water to a stock solution of 200 µg/mL. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% (W/V) HSA or BSA) is recommended for further dilution and long term storage.
NCBI Gene Symbol: SIGLEC6
Gene ID: 946
NCBI Accession: O43699
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK293 cells |
Purity by SDS-PAGE: |
>92% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
<1 EU/μg by LAL method |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Measured by its ability to bind biotinylated Neu5Ac alpha 2-6GalNAc alpha (sialyl-Tn). |
Results: |
N/A |
Molecular Weight: |
60.3 kDa |
Storage Temperature: |
+4°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Dry powder |
Handling: |
Centrifuge the vial prior to opening. |