Description
Human CellExp™ PVRIG, Fc Tag, Cynomolgus recombinant is available at Gentaur for Next week delivery.
act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
Biomolecule/Target:
Alternates names: C7orf15, CD112R, C7orf15MGC138295, MGC104322, MGC138297, MGC2463, Poliovirus receptor-related immunoglobulin domain-containing protein, transmembrane protein PVRIG
Synonyms: C7orf15, CD112R, C7orf15MGC138295, MGC104322, MGC138297, MGC2463, Poliovirus receptor-related immunoglobulin domain-containing protein, transmembrane protein PVRIG
Background Information: Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
NCBI Gene Symbol: PVRIG
Gene ID: 102127364
NCBI Accession: A0A2K5WVV8
Additional Information
Size: |
50 µg |
Adwords: |
False |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Cynomolgus |
Recombinant: |
True |
Source: |
HEK 293 Cells |
Purity by SDS-PAGE: |
>95% |
Assay: |
SDS-PAGE |
Endotoxin Level: |
Less than 1.0 EU per μg by the LAL method. |
Molecular Weight: |
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.1 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Storage Temperature: |
-20ºC |
Shelf Life: |
12 months |
Appearance: |
Lyophilized powder |
Handling: |
Centrifuge the vial prior to opening. |