Human CellExp™ IL-12, Human Recombinant

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SKU:
6467-50
€185
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Description

Human CellExp™ IL-12, Human Recombinant is available at Gentaur for Next week delivery.

A T cell-stimulating factor

Biomolecule/Target:

Alternates names: NKSF, CTL maturation factor (TCMF), Cytotoxic lymphocyte maturation factor (CLMF), TSF, Edodekin-alpha, IL-12.

Synonyms: Human Cellexp Human Recombinant IL-12

Background Information: IL-12 is a potent regulator of cell mediated immune responses and in induces IFN-Ɣ production by NK and T cells. It is produced by activated monocytes/macrophage cells, B-lymphocytes, and connective tissue type mast cells. Among its biological activities, IL-12 promotes the growth and activity of activated NK, CD4+, and CD8+ cells and induce the development of IFN-Ɣ producing Th1 cells.

Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

NCBI Gene Symbol: IL12A

Gene ID: 3592

NCBI Accession: P29459

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Additional Information

Size:
50 µg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
China
Gene Source:
Human
Recombinant:
Yes
Source:
Human 293 cell expressed
Purity by SDS-PAGE:
> 95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
< 1.0 EU per 1 μg of protein
Activity (Specifications/test method):
N/A
Biological activity:
ED₅₀ is typically 0.1 to 0.5 ng/mL ng/mL. The specific activity was determined by the dose-dependent release of IFN-gamma from the human NK92 cell line in presence of 20 ng/mL rIL-2.
Results:
0.1 to 0.5 ng/ml
Molecular Weight:
57 kDa, heterodimer, glycosylated
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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