Description
Human CellExp™ IL-12, Human Recombinant is available at Gentaur for Next week delivery.
A T cell-stimulating factor
Biomolecule/Target:
Alternates names: NKSF, CTL maturation factor (TCMF), Cytotoxic lymphocyte maturation factor (CLMF), TSF, Edodekin-alpha, IL-12.
Synonyms: Human Cellexp Human Recombinant IL-12
Background Information: IL-12 is a potent regulator of cell mediated immune responses and in induces IFN-Ɣ production by NK and T cells. It is produced by activated monocytes/macrophage cells, B-lymphocytes, and connective tissue type mast cells. Among its biological activities, IL-12 promotes the growth and activity of activated NK, CD4+, and CD8+ cells and induce the development of IFN-Ɣ producing Th1 cells.
Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
NCBI Gene Symbol: IL12A
Gene ID: 3592
NCBI Accession: P29459
Additional Information
Size:  | 
                                                    50 µg  | 
                                                
Country of Manufacturing Origin:  | 
                                                    USA  | 
                                                
Country of Animal Origin:  | 
                                                    China  | 
                                                
Gene Source:  | 
                                                    Human  | 
                                                
Recombinant:  | 
                                                    Yes  | 
                                                
Source:  | 
                                                    Human 293 cell expressed  | 
                                                
Purity by SDS-PAGE:  | 
                                                    > 95%  | 
                                                
Assay:  | 
                                                    SDS-PAGE  | 
                                                
Purity:  | 
                                                    N/A  | 
                                                
Assay 2:  | 
                                                    N/A  | 
                                                
Endotoxin Level:  | 
                                                    < 1.0 EU per 1 μg of protein  | 
                                                
Activity (Specifications/test method):  | 
                                                    N/A  | 
                                                
Biological activity:  | 
                                                    ED₅₀ is typically 0.1 to 0.5 ng/mL ng/mL. The specific activity was determined by the dose-dependent release of IFN-gamma from the human NK92 cell line in presence of 20 ng/mL rIL-2.  | 
                                                
Results:  | 
                                                    0.1 to 0.5 ng/ml  | 
                                                
Molecular Weight:  | 
                                                    57 kDa, heterodimer, glycosylated  | 
                                                
Storage Temperature:  | 
                                                    -20°C  | 
                                                
Shelf Life:  | 
                                                    12 months  | 
                                                
Concentration:  | 
                                                    N/A  | 
                                                
Appearance:  | 
                                                    Lyophilized  | 
                                                
Handling:  | 
                                                    Centrifuge the vial prior to opening.  |