Human CellExp™ IgG2 Fc, Human Recombinant

Human CellExp™ IgG2 Fc, Human Recombinant is available at Gentaur for Next week delivery.

Constant region of immunoglobulin heavy chains.

Biomolecule/Target: IGHG2

Alternates names: IgG Fc

Synonyms: IgG Fc

Background Information: Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis. Ig gamma-2 chain Fc region contains two constant regions of IgG2 H chain (CH2, CH3).

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

NCBI Gene Symbol: IGHG2

Gene ID: 3501

NCBI Accession: P01859