Human CellExp™ DLK1, Human Recombinant

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SKU:
P1166-10
€185
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Description

Human CellExp™ DLK1, Human Recombinant is available at Gentaur for Next week delivery.

Plays role in neuroendocrine differentiation.

Biomolecule/Target: DLK1

Alternates names: Protein Delta Homolog 1, Fetal Antigen 1, Preadipocyte Factor 1, Pref-1, FA1

Synonyms: Protein Delta Homolog 1, Fetal Antigen 1, Preadipocyte Factor 1, Pref-1, FA1

Background Information: The transmembrane and secreted protein delta-like 1 homolog (DLK1; Protein delta homolog 1; Preadipocyte factor 1; Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-α converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.

Reconstitution Instructions: Reconstitute with 100 µl sterile water.

NCBI Gene Symbol: DLK1

Gene ID: 8788

NCBI Accession: P80370

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Additional Information

Size:
10 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
HEK293 cells
Purity by SDS-PAGE:
> 98%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
< 1.0 EU per/μg
Activity (Specifications/test method):
Measured by inhibition of adipogenesis of 3T3L-1 cells
Biological activity:
Inhibits adipogenesis of 3T3L-1 cells
Results:
N/A
Molecular Weight:
65 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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