Human CellExp™ Dermatopontin, Human Recombinant

Human CellExp™ Dermatopontin, Human Recombinant is available at Gentaur for Next week delivery.

Tyrosine-rich acidic matrix protein that communicate between the dermal fibroblast cell surface and its extracellular matrix environment

Biomolecule/Target: DPT

Alternates names: Dermatopontin, Tyrosine-rich acidic matrix protein, TRAMP and DPT

Synonyms: Dermatopontin, Tyrosine-rich acidic matrix protein, TRAMP and DPT

Background Information: Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal muscle, brain and pancreas. It seems to mediate adhesion by cell surface integrin binding. DPT may serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. DPT can enhance TGFB1 activity through interaction with decorin. In addition, DPT accelerates collagen fibril formation, stabilizes collagen fibrils against low-temperature dissociation and inhibits cell proliferation.

Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 100 µg/ml.

NCBI Gene Symbol: DPT

Gene ID: 1805

NCBI Accession: Q07507