Human CellExp™ BCMA / TNFRSF17, Fc Tag, Human recombinant

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SKU:
P1326-50
€185
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Description

Human CellExp™ BCMA / TNFRSF17, Fc Tag, Human recombinant is available at Gentaur for Next week delivery.

A member of the TNF receptor superfamily

Biomolecule/Target: TNFRSF17

Alternates names: TNFRSF17, CD269, BCM, BCMA

Synonyms: TNFRSF17, CD269, BCM, BCMA

Background Information: Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.

Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 50 μg/ml.

NCBI Gene Symbol: TNR17

Gene ID: 608

NCBI Accession: Q02223

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Additional Information

Size:
50 µg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
HEK 293 cells
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
< 1 EU/μg
Activity (Specifications/test method):
Measured by its binding ability in a functional ELISA.
Biological activity:
Immobilized Biotinylated Human BAFF, His Tag at 1 μg/mL (100 μL/well) can bind Human BCMA, Fc Tag with a linear range of 0.1-0.8 ng/mL.
Results:
N/A
Molecular Weight:
32 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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