Human CellExp™ ADIPOQ /Adiponectin /ACRP30, human recombinant

Human CellExp™ ADIPOQ /Adiponectin /ACRP30, human recombinant is available at Gentaur for Next week delivery.

Involved in the control of fat metabolism and insulin sensitivity

Biomolecule/Target: Adiponectin

Alternates names: ADIPOQ, Adiponectin, ACDC, ACRP30, APM1, GBP28

Synonyms: ADIPOQ, Adiponectin, ACDC, ACRP30, APM1, GBP28

Background Information: Adiponectin also referred to as GBP-28, APM1, ADIPOQ, ACDC and Acrp30, is a secreted protein which contains one C1q domain (commonly called the globular domain) and one collagen-like domain. Adiponectin / ADIPOQ is synthesized exclusively by adipocytes and secreted into plasma. ADIPOQ is important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Acrp30 Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway and may play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

NCBI Gene Symbol: ADIPOQ

Gene ID: 9370

NCBI Accession: Q15848