Factor VII, Human Plasma

Factor VII, Human Plasma is available at Gentaur for Next week delivery.

Responsible for starting a cascade of proteolytic events that lead to thrombin generation, fibrin deposition, and platelet activation.

Biomolecule/Target: Factor VII

Alternates names: Proconvertin, Serum prothrombin conversion accelerator.

Synonyms: Proconvertin, Serum prothrombin conversion accelerator.

Background Information: Human factor VII is a single chain, vitamin K-dependent, plasma glycoprotein which is synthesized in the liver. Prior to secretion into the blood, post translational modification by a vitamin K-dependent carboxylase produces ten-carboxyglutamic acid (gla) residues located in the NH2-terminal portion of the molecule, which facilitate cell membrane binding. Factor VII is proteolytically activated to the serine protease, factor VIIa, during coagulation. Factor VII can be activated by thrombin, factor IXa, factor Xa or factor XIIa.

Reconstitution Instructions: N/A

NCBI Gene Symbol: F7

Gene ID: 2155

NCBI Accession: P08709