Exodus-2, Mouse Recombinant

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SKU:
7681-20
€185
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Description

Exodus-2, Mouse Recombinant is available at Gentaur for Next week delivery.

A chemokine which inhibits hemopoiesis and stimulates chemotaxis

Biomolecule/Target: CCL21

Alternates names: C-C motif chemokine 21, 6Ckine, Beta-chemokine exodus-2, Secondary lymphoid-tissue chemokine, SLC, Small-inducible cytokine A21

Synonyms: C-C motif chemokine 21, 6Ckine, Beta-chemokine exodus-2, Secondary lymphoid-tissue chemokine, SLC, Small-inducible cytokine A21

Background Information: Exodus-2, also known as CCL21 and 6Ckine, is a novel chemokine produced at high levels in human lymph node tissue and the spleen. 6Ckine signals through the CCR7 receptor to recruit thymocytes and activated T cells in vitro, but is not known to be chemotactic for monocytes. Human and mouse Exodus-2 share > 85% amino acid homology. Recombinant mouse Exodus-2 is a nonglycosylated protein, containing 110 amino acids, with a molecular weight of 12 kDa.

Reconstitution Instructions: Recommended reconstitution in sterile water at a concentration of 0.1 mg/mL

NCBI Gene Symbol: CCL21

Gene ID: 18829

NCBI Accession: P84444

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Additional Information

Size:
20 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Mouse
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
≤ 1 EU/μg protein
Activity (Specifications/test method):
N/A
Biological activity:
The activity is determined by its ability to chemoattract 5-10 day old cultures of human peripheral blood lymphocytes at concentrations between 200 ng/mL- 600 ng/mL.
Results:
200 ng/mL- 600 ng/mL.
Molecular Weight:
12 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized powder
Handling:
Centrifuge the vial prior to opening.
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