Description
Epigen (EPGN), human recombinant is available at Gentaur for Next week delivery.
Promotes the growth of epithelial cells
Biomolecule/Target:
Alternates names: EPG, Epigen, PRO9904, ALGV3072, FLJ75542, EPGN, Epithelial mitogen,
Synonyms: EPG, Epigen, PRO9904, ALGV3072, FLJ75542, EPGN, Epithelial mitogen,
Background Information: EPGN is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. EPGN is produced in numerous tissues, including the testis, liver, heart and in certain tumor cells. EPGN is mitogenic for fibroblasts and epithelial cells. Human EPGN is originally synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence. Recombinant Human epigen produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 72 amino acids and having a molecular mass of 7.9 kDa. Epigen is purified by proprietary chromatographic techniques.
Reconstitution Instructions: Reconstitute in sterile dH₂O not less than 100 μg/ml.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
NCBI Gene Symbol: EPGN
Gene ID: 255324
NCBI Accession: Q6UW88
Additional Information
Size: |
25 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥98% |
Assay: |
SDS-PAGE |
Purity: |
≥98% |
Assay 2: |
HPLC |
Endotoxin Level: |
<0.1 ng/μg |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells. The expected ED₅₀ for this effect is 150-300 ng/ml. |
Results: |
150-300 ng/ml |
Molecular Weight: |
7.9 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |