Description
Eotaxin-2/CCL24, murine recombinant is available at Gentaur for Next week delivery.
A CC chemokine that signals through the CCR3 receptor
Biomolecule/Target: CCL24
Alternates names: CCL24
Synonyms: CCL24
Background Information: Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the murine homolog, without C-terminal truncation). Recombinant murine Eotaxin-2 is a 10.3 kDa protein containing 93 amino acid residues.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
NCBI Gene Symbol: CCL24
Gene ID: 56221
NCBI Accession: Q9JKC0
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Murine |
Recombinant: |
Yes |
Source: |
E. coli. |
Purity by SDS-PAGE: |
≥98% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
HPLC |
Endotoxin Level: |
< 0.1 ng/μg of protein (<1EU/μg). |
Activity (Specifications/test method): |
Determined by its ability to chemoattract murine lymphocytes using a concentration range of 10.0-100.0 ng/ml. |
Biological activity: |
Determined by its ability to chemoattract murine lymphocytes using a concentration range of 10.0-100.0 ng/ml. |
Results: |
N/A |
Molecular Weight: |
10.3 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized powder |
Handling: |
Centrifuge the vial prior to opening. |