Elastase, Human Neutrophil

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SKU:
4716-100
€185
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Description

Elastase, Human Neutrophil is available at Gentaur for Next week delivery.

Breaks down elastin

Biomolecule/Target:

Alternates names: Leukocyte Elastase, ELA2

Synonyms: Leukocyte Elastase, ELA2

Background Information: Elastase, like trypsin and chymotrypsin, is a serine protease that also hydrolyses amides and esters. It is produced in the pancreas as an inactive zymogen, proelastase, and activated in the duodenum by trypsin. Elastase is distinctive in that it acts upon elastin.This enzyme degrades elastin, collagen, and proteoglycan and has been implicated in the development of pulmonary emphesema and rheumatoid arthritis.

Reconstitution Instructions: Deionized H₂O

NCBI Gene Symbol: ELANE

Gene ID: 1991

NCBI Accession: P08246

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Additional Information

Size:
100 µg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
No
Source:
Human Neutrophil
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
N/A
Activity (Specifications/test method):
20-22 units per mg protein. One unit is defined as the amount of enzyme that hydrolyzes one micromole of Meo-Suc-Ala-Pro-Val-pNA per minute at 25°C in 100 mM Tris-HCl, pH 7.5, with 500 mM NaCl.
Molecular Weight:
29.5 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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