CSTB, human recombinant

CSTB, human recombinant is available at Gentaur for Next week delivery.

An anti-protease implicated in myoclonus epilepsy.

Biomolecule/Target: CSTB

Alternates names: Cystatin-B, Stefin B, PME, CST7

Synonyms: Cystatin-B, Stefin B, PME, CST7

Background Information: CSTB, also known as Cystatin B is an anti-protease implicated in myoclonus epilepsy, a degenerative disease of the central nervous system. The cystatin superfamily encompasses proteins that contain multiple cystatin like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. This protein is able to form a dimer stabilized by noncovalent forces and is thought to play a role in protecting against the proteases leaking from lysosomes. In cells, CSTB is located in the lysosomes and the cytoplasm, but also in the nucleus.

Reconstitution Instructions: In 20 mM Tris-HCl buffer (pH8.0) containing 50mM NaCl.

NCBI Gene Symbol: CSTB

Gene ID: 1476

NCBI Accession: NP_000091