CDK2AP1 Protein, Human Recombinant

CDK2AP1 Protein, Human Recombinant is available at Gentaur for Next week delivery.

Biomolecule/Target:

Alternates names: CDKA1,CDK2 associated protein 1,CDK2 A1,DOC1,Cyclin-dependent kinase 2

Synonyms: CDKA1,CDK2 associated protein 1,CDK2 A1,DOC1,Cyclin-dependent kinase 2

Background Information: Cyclin-dependent kinase 2-associated protein 1 (CDK2AP1), a growth suppressor that negatively regulates CDK2 activity, has been implicated in various types of cancer. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation.

Reconstitution Instructions:

NCBI Gene Symbol: O14519

Gene ID: 8099

NCBI Accession: NP_004633, O14519