CD3E, human recombinant

CD3E, human recombinant is available at Gentaur for Next week delivery.

Plays a role in coupling antigen recognition to several intracellular signal-transduction pathways

Biomolecule/Target: CD3E

Alternates names: T-cell surface glycoprotein CD3 epsilon chain, T3E, TCRE

Synonyms: T-cell surface glycoprotein CD3 epsilon chain, T3E, TCRE

Background Information: CD3E is the CD3-epsilonpolypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. Recombinant human CD3E protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Reconstitution Instructions: N/A

NCBI Gene Symbol: CD3E

Gene ID: 916

NCBI Accession: P07766