BID, Human Recombinant

BID, Human Recombinant is available at Gentaur for Next week delivery.

Pro-apoptotic Bcl-2 protein

Biomolecule/Target:

Alternates names: BH3-interacting domain death agonist, p22 BID, p11 BID

Synonyms: BH3-interacting domain death agonist, p22 BID, p11 BID

Background Information: BID is a pro-apoptotic Bcl-2 protein containing only the BH3 domain. In response to apoptotic signaling, BID interacts with another Bcl-2 family protein, Bax, leading to the insertion of Bax into the outer mitochondrial membrane. Bax is believed to induce the opening of the mitochondrial voltage-dependent anion channel. This results in the release of cytochrome c and other pro-apoptotic factors from the mitochondria leading to activation of caspases. Recombinant BID protein was expressed in E. coli and purified by using conventional chromatography techniques.

Reconstitution Instructions:

NCBI Gene Symbol: BID

Gene ID: 637

NCBI Accession: P55957