Amphiregulin, Human Recombinant

Amphiregulin, Human Recombinant is available at Gentaur for Next week delivery.

Stimulates growth of keratinocytes, epithelial cells and some fibroblasts

Biomolecule/Target: Amphiregulin

Alternates names: AR, AREG, Colorectum cell-derived growth factor (CRDGF)

Synonyms: AR, AREG, Colorectum cell-derived growth factor (CRDGF)

Background Information: Amphiregulin is an EGF related growth factor that signals through the EGF/TGF-a receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, amphiregulin’s extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. Recombinant human Amphiregulin is a 11.3 kDa glycoprotein consisting of 98 amino acid residues.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

NCBI Gene Symbol: AREG

Gene ID: 374

NCBI Accession: P15514