Description
AKR1D1, human recombinant is available at Gentaur for Next week delivery.
Plays an important role in the metabolism of drugs, carcinogens and reactive aldehydes
Biomolecule/Target: AKR1D1
Alternates names: Aldo-keto reductase family 1, member D1, 3o5bred, CBAS2, SRD5B1
Synonyms: Aldo-keto reductase family 1, member D1, 3o5bred, CBAS2, SRD5B1
Background Information: Aldo-keto reductase family 1, member D1, also known as AKR1D1, is a member of the AKR superfamily. The AKR family of proteins is soluble NADPH oxidoreductases. They play important roles in the metabolism of drugs, carcinogens and reactive aldehydes. AKR1D1 is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones which carry a delta (4)-3-one structure. AKR1D1 is highly expressed in liver, colon and testis. Deficiency of this enzyme may contribute to hepatic dysfunction. Recombinant human AKR1D1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Reconstitution Instructions: N/A
NCBI Gene Symbol: AKR1D1
Gene ID: 6718
NCBI Accession: P51857
Additional Information
Size: |
100 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥90% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
N/A |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
39.5 kDa (346 aa, 1-326 aa + His Tag), confirmed by MALDI-TOF. |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
0.5 mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |
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