Active Recombinant Human beta-Secretase 1 - BACE-1

Active Recombinant Human beta-Secretase 1 - BACE-1 is available at Gentaur for Next week delivery.

A protease important in the formation of myelin sheaths in PNC.

Biomolecule/Target:

Alternates names: Beta-secretase 1, Aspartyl protease 2, ASP2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, Aspartic-like protease 56 kDa, Aspartyl protease 1, Beta-site amyloid precursor protein cleaving enzyme 2, Down region aspartic protease, Memapsin-1, Membrane-associated aspartic protease 1, Theta-secretase

Synonyms: Beta-Secretase

Background Information: β-Secretase, also called BACE1 (β-site of APP cleaving enzyme) or memapsin-2 is an aspartic-acid protease important in the pathogenesis of Alzheimer's disease, and in the formation of myelin sheaths in peripheral nerve cells. The transmembrane protein, contains two active site aspartate residues in its extracellular protein domain and may function as a dimer..

Reconstitution Instructions: Use 20 µl sterile D.I. water to dissolve 10 µg of protein for a final conc of 0.5 µg/µl. For further dilution, use 10 mM Tris, pH 8.0.

NCBI Gene Symbol: BACE1

Gene ID: 23621

NCBI Accession: P56817