PKM Polyclonal Antibody

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SKU:
CAC07314
Availability:
Next week delivery
€33,400
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Description

PKM Polyclonal Antibodyis available at Gentaur for next week delivery.

Specificity:

Alternative Names: P14618

Immunogen: Recombinant Human Pyruvate kinase PKM protein (2-192AA)

Technical Notes: For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Restriction:

Comments: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.

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Additional Information

Species Reactivity:
Human
Size:
100ug
Host:
Rabbit
Clonality:
Polyclonal
Concentration:
-20°C
Storage:
1 year
Expiry Date:
Ice packs
Shipping Condition:
Conjugation service and the corresponding secondary antibody are available.
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