Phospho-hnRPD (Ser83) Antibody

Phospho-hnRPD (Ser83) Antibodyis available at Gentaur for Next week Delivery.

Description: Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation.

Immunogen Sequence:/

Target Alternative Name:ARE binding protein AUFI type A; AU-rich element RNA-binding protein 1; AUF; AUF1; AUF1A; Heterogeneous nuclear ribonucleoprotein D0; hnRNP D; hnRNP D0; Hnrnpd; hnRNPD0; HNRPD; HNRPD_HUMAN; P37

Species Reactivities:Rat, Mouse, Human

Tag Line:Polyclonal antibody to detect Phospho-hnRPD (Ser83)

Formulation:In phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol

Purification: Affinity purified

Application:Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blotting, ELISA

Positive Control:/

Application And Usages:WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500, ELISA (peptide) 1:20000-1:40000

Handling:The antibody solution should be gently mixed before use.