Phospho-Gab2 (Tyr452) Antibody

Phospho-Gab2 (Tyr452) Antibodyis available at Gentaur for Next week Delivery.

Description: This gene is a member of the GRB2-associated binding protein (GAB) gene family and is similar to the GAB1 gene. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

Immunogen Sequence:A synthesized peptide derived from human Gab2 around the phosphorylation site of Tyrosine 452

Target Alternative Name:GRB2-associated-binding protein 2, GRB2-associated binder 2, Growth factor receptor bound protein 2-associated protein 2, pp100, KIAA0571, GAB2

Species Reactivities:Rat, Mouse, Human

Tag Line:Polyclonal antibody to detect endogenous levels of Phospho-Gab2 (Tyr452) in human sample

Formulation:In phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.

Purification: Affinity purified

Application:Western Blotting, ELISA

Positive Control:/

Application And Usages:WB 1:500-1:2000, ELISA (peptide) 1:20000-1:40000

Handling:The antibody solution should be gently mixed before use.