Phospho-Cofilin (Ser3) Antibody

Phospho-Cofilin (Ser3) Antibodyis available at Gentaur for Next week Delivery.

Description: Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration.

Immunogen Sequence:Synthesized peptide derived from human Cofilin around the phosphorylation site of S3

Target Alternative Name:Cofilin-1, 18 kDa phosphoprotein, p18, Cofilin, non-muscle isoform, CFL1, CFL

Species Reactivities:Human, Mouse, Rat

Tag Line:Polyclonal antibody to detect endogenous levels of Cofilin (Ser3) in human, mouse and rat samples

Formulation:In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Purification: Affinity-chromatography using epitope-specific immunogen

Application:WB, IHC, ELISA

Positive Control:WB: COLO205 cell lysate

Application And Usages:WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000

Handling:The antibody solution should be gently mixed before use