PCSK9 Antibody

PCSK9 Antibodyis available at Gentaur for Next week Delivery.

Description: Proprotein convertase subtilisin/kexin type 9 (PCSK9), is an enzyme which in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A (EGF-A) domain of the low-density lipoprotein receptor (LDLR), inducing LDLR degradation. PCSK9 may also have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a rare form of autosomal dominant familial hypercholesterolemia (HCHOLA3).

Immunogen Sequence:A synthetic peptide corresponding to a sequence at the C-terminal (671-687aa AVTAVAICCRSRHLAQA) of human PCSK9.

Target Alternative Name:PCSK9, FH3, HCHOLA3, LDLCQ1, NARC1, PC9, FH3; NARC-1; HCHOLA3; PC9; Proprotein convertase 9; Subtilisin/kexin-like protease PC9; Hypercholesterolemia, autosomal dominant 3; Neural apoptosis-regulated convertase 1;

Species Reactivities:Human

Tag Line:Polyclonal Antibody to detect PCSK9 in human samples.

Formulation:Lyophilized from 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3.

Purification: Immunogen affinity purified.

Application:WB, IHC-P

Positive Control:Western blot: A549, HeLa, U87, PANC Cell Lysate. IHC-P: Human Intestinal Cancer Tissue.

Application And Usages:WB, IHC-P

Handling:The antibody solution should be gently mixed before use.