NPLOC4 Antibody

(No reviews yet) Write a Review
SKU:
CAF20379
Availability:
Next week delivery
€32,900
Frequently bought together:

Description

NPLOC4 Antibodyis available at Gentaur for next week delivery.

Specificity: 55666

Alternative Names:

Immunogen: A synthesized peptide derived from human NPLOC4.

Technical Notes: The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity). Acts as a negative regulator of type I interferon production via the complex formed with VCP and UFD1, which binds to DDX58/RIG-I and recruits RNF125 to promote ubiquitination and degradation of DDX58/RIG-I (PubMed:26471729).

Application: WB

Restriction:

Comments: Ice packs

View AllClose

Additional Information

Species Reactivity:
Human,Mouse,Rat
Size:
100ug
Host:
Rabbit
Clonality:
Polyclonal
Concentration:
NPLOC4
Storage:
1mg/ml
Expiry Date:
-20°C
Shipping Condition:
1 year
Uniprot:
Q8TAT6
View AllClose

0 Reviews

View AllClose