Description
L1 Polyclonal Antibodyis available at Gentaur for next week delivery.
Specificity:
Alternative Names: P06794
Immunogen: Recombinant HPV18 Major capsid protein L1 protein (1-568AA)
Technical Notes: For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Application: ELISA, WB; Recommended dilution: WB:1:1000-1:5000
Restriction:
Comments: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4; Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on the basement membrane to provide initial virion attachment to target cells. Basement membrane is exposed only after epithelium trauma. Additionally, the alpha6 integrin complexed with either beta1 or beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, integrin complexed with beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, the virion enters the host cell via clathrin-mediated endocytosis and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.
Additional Information
Species Reactivity: |
Human papillomavirus type 18 |
Size: |
100ug |
Host: |
Rabbit |
Clonality: |
Polyclonal |
Concentration: |
-20°C |
Storage: |
1 year |
Expiry Date: |
Ice packs |
Shipping Condition: |
Conjugation service and the corresponding secondary antibody are available. |