Description
IVNS1ABP Antibodyis available at Gentaur for next week delivery.
Specificity: 10625
Alternative Names:
Immunogen: A synthesized peptide derived from human IVNS1ABP.
Technical Notes: Involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats (By similarity). Protects cells from cell death induced by actin destabilization (By similarity). Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription (PubMed:16582008). In addition, functions as a negative regulator of BCR(KLHL20) E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors (PubMed:25619834). Inhibits pre-mRNA splicing (in vitro) (PubMed:9696811).
Application: WB
Restriction:
Comments: Ice packs
Additional Information
Species Reactivity: |
Human,Mouse,Rat |
Size: |
100ug |
Host: |
Rabbit |
Clonality: |
Polyclonal |
Concentration: |
IVNS1ABP |
Storage: |
1mg/ml |
Expiry Date: |
-20°C |
Shipping Condition: |
1 year |
Uniprot: |
Q9Y6Y0 |
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