Description
GEMIN7 Polyclonal Antibodyis available at Gentaur for next week delivery.
Specificity:
Alternative Names: Q9H840
Immunogen: Recombinant Human Gem-associated protein 7 protein (1-131AA)
Technical Notes: For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Application: ELISA, WB; Recommended dilution: WB:1:1000-1:5000
Restriction:
Comments: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
Additional Information
Species Reactivity: |
Human |
Size: |
100ug |
Host: |
Rabbit |
Clonality: |
Polyclonal |
Concentration: |
-20°C |
Storage: |
1 year |
Expiry Date: |
Ice packs |
Shipping Condition: |
Conjugation service and the corresponding secondary antibody are available. |