DNMT3A polyclonal antibody

DNMT3A polyclonal antibodyis available at Gentaur for Next week Delivery.

Description: DNMT3A catalyzes the genome wide de novo methylation of CpG residues. DNA methylation on CpG residues by DNMT3A regulates gene expression and is essential for development. DNMT3A is strongly expressed in embryonic stem cells, but low in adult somatic cells. DNA methylation is coordinated with methylation of histones. DNMT3A binds to SETDB1 and HDAC1, and is involved in the repression of transcription from promoters containing an E2F binding site.

Immunogen Sequence:Polyclonal antibody raised in rabbit against human DNMT3A, (DNA methyltransferase 3A), using a KLH-conjugated synthetic peptide corresponding to amino acids 92-106.

Target Alternative Name:DNA Methyltransferase 3a

Species Reactivities:Human.

Tag Line:Polyclonal Antibody to detect DNMT3a in human samples.

Formulation:In PBS with 0.05% sodium azide and 0.05% ProClin 300.

Purification: Affinity Purified

Application:Western blot, ELISA, IP.

Positive Control:Western blot: HEK 293 T cells, ELISA: Peptides, IP: HEK 293 T cells.

Application And Usages:Western Blot: 1:2,500, ELISA: 1:100, IP: 2 µg/IP.

Handling:The antibody solution should be gently mixed before use.