TGF-beta Receptor I Antibody

TGF-beta Receptor I Antibodyis available at Gentaur for Next week Delivery.

Description: TGF-β (Transforming growth factor-beta superfamily members are critical regulators of cell proliferation, differentiation, morphogenesis, and pathogenesis. TGF-beta receptor is a serine/threonine kinase receptor complex that consists of two distinct transmembrane proteins known as type I and type II receptors. In response to ligand binding, the type II receptors form a stable complex with the type I receptors allowing phosphorylation and thus activation of the type I receptor kinases.

Immunogen Sequence:Synthetic peptide surrounding amino acid 411 of human TGF-β Receptor I

Target Alternative Name:Transforming growth factor beta receptor I, TGFR1, TGFR-1, TGFR 1, TGF beta receptor type 1, TbetaR I , Serine/threonine-protein kinase receptor R4, SKR4, SKR 4, SKR-4

Species Reactivities:Human

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Formulation:30 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot

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Application And Usages:Western blotting (0.5-4 µg/ml) and Immunohistochemistry (5 µg/ml). However, the optimal conditions should be determined individually. antibody detects 30 and 55 kDa isoforms of TGF-β Receptor I on SDS-PAGE immunoblots in samples from human, mouse, rat, pig and bovine origins.

Handling:The antibody solution should be gently mixed before use.