Sox-2 Antibody

Sox-2 Antibodyis available at Gentaur for Next week Delivery.

Description: Sox genes encode for transcriptional regulators that are involved in the early embryonic develpoment and in the determination of cell fate. Sox2 is also known as SRY (sex determining region Y)-box2, contain genes that encode for the H mg-box domain that is responsible for DNA binding activity. Mutation of Sox2 genes is link to optic nerve hypoplasia and anophthalmia, a severe form of eye deformity.

Immunogen Sequence:Synthetic peptide surrounding amino acid 301 of human Sox2

Target Alternative Name:Sox2, Sox 2, SRY-box containing gene 2, sex determining region Y box-2, SRY related H mg box 2, Transcription factor SOX 2

Species Reactivities:Human, mouse, rat, pig, bovine, dog, sheep

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Formulation:30 µg (0.5 mg/ml) antigen affinity purified rabbit anti-Sox-2polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% Thimerosal.

Purification: Affinity purified

Application:Western blot

Positive Control:/

Application And Usages:Western blotting (0.5-1 µg/ml). However, the optimal conditions should be determined individually. Other applications have not been tested. The antibody detects ~35kDa of Sox2 in samples from mouse origins.

Handling:The antibody solution should be gently mixed before use.