Rho Kinase Alpha Antibody

Rho Kinase Alpha Antibodyis available at Gentaur for Next week Delivery.

Description: Rho-associated protein kinase 2 (ROCK2), or Rho kinase alpha, is a serine-threonine protein kinase that plays an important role in cellular apoptosis, growth, cell motility and cell contraction. ROCK2 shares an overall 65% homology in amino acid sequence with ROCK1. The ROCK1 and ROCK2 isoforms are products of two separate genes. Both ROCK1 and ROCK2 are downstream targets of the Rho A small GTP-binding protein. As downstream effectors of RhoA, ROCK1 and ROCK2 mediate changes in the actin cytoskeleton via phosphorylation of target proteins such as the MBS subunit of MLCP, MLC, ERM proteins, protein LIM kinase and adducin.

Immunogen Sequence:Synthetic peptide of human Rho Kinase Alpha

Target Alternative Name:Rho Kinase, ROCK2, ROCK-2, ROCKII, ROCK-II, Rho-associated, Coiled-coil containing protein Kinase 2, ROK-alpha, Rho Kinase Alpha, KIAA0619

Species Reactivities:Human, mouse

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Formulation:100 µl affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA and 0.02% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunoprecipitation

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Application And Usages:Western blotting (1:1000 – 1:2500) and Immunoprecipitation. However, the optimal concentrations should be determined individually. The antibody recognizes the Rho Kinase Alpha of human and mouse origins. Reactivity to other species has not been tested.

Handling:The antibody solution should be gently mixed before use.