PLC gamma 2 Antibody

PLC gamma 2 Antibodyis available at Gentaur for Next week Delivery.

Description: PLC (Phosphoinositide-specific phospholipase C) plays a significant role in transmembrane signaling. Four members of PLCs have been identified: PLCβ, PLCg, PLCd, and PLCe. In response to extracellular stimuli (e.g., hormone, growth factors, neurotransmitters), PLC hydrolizes phosphatidylinositol 4,5-biphosphate (PIP2) into two secondary messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PLCg2 is engaged in antigen-dependent signaling in B-cells and collagen-dependent signaling in platelets.

Immunogen Sequence:Synthetic peptide surrounding amino acid 1252 of human PLCg2

Target Alternative Name:PLC2 , PLC148 , PLC-II , PLC-148, inositoltrisphosphohydrolase

Species Reactivities:Human

Tag Line:/

Formulation:30 µg (0.5 mg/ml) protein A affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunohistochemistry

Positive Control:Western Blot: Jurkat cell lysate . IHC: Brain and Cortex tissue

Application And Usages:Western blotting (0.5-4 µg/ml) and Immunohistochemistry (5 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 139 kDa human PLCg2. Jurkat cell lysate can be used as a positive control. Reactivity to other species has not been determined.

Handling:The antibody solution should be gently mixed before use.