Phospho RPS6 (Ser235) Antibody

Phospho RPS6 (Ser235) Antibodyis available at Gentaur for Next week Delivery.

Description: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Immunogen Sequence:KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human RPS6

Target Alternative Name:40S ribosomal protein S6; Phosphoprotein NP33

Species Reactivities:Bovine, Sheep, Zebrafish, Rat, Chicken, Monkey, Mouse, Human

Tag Line:Affinity purified rabbit polyclonal antibody to detect phosphorylation of RPS6 at Ser235 in human, mouse, rat, bovine, chicken, monkey, sheep and zebrafish samples

Formulation:In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application:Immunofluorescence (IF), Western Blotting

Positive Control:/

Application And Usages:WB 1:500 - 1:1000, IF 1:100 - 1:500

Handling:The antibody solution should be gently mixed before use.