Phospho p38 (Tyr323) Antibody

Phospho p38 (Tyr323) Antibodyis available at Gentaur for Next week Delivery.

Description: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Immunogen Sequence:KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human p38

Target Alternative Name:CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein 2; Mitogen-activated protein kinase p38 alpha; MAP kinase p38 alpha; Stress-activated protein kinase 2a; SAPK2a

Species Reactivities:Bovine, Sheep, Dog, Rat, Mouse, Human

Tag Line:Affinity purified rabbit polyclonal antibody to detect phosphorylation of p38 at Tyr323 in human, mouse, rat, bovine, dog and sheep samples

Formulation:In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application:Immunohistochemistry (IHC), Western Blotting

Positive Control:/

Application And Usages:WB 1:500 - 1:1000, IHC 1:100 - 1:200

Handling:The antibody solution should be gently mixed before use.