Phospho HDAC5 (Ser498) Antibody

Phospho HDAC5 (Ser498) Antibodyis available at Gentaur for Next week Delivery.

Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.

Immunogen Sequence:KLH-conjugated synthetic peptide targeting a sequence within the center region of human HDAC5.

Target Alternative Name:KIAA0600; Histone deacetylase 5; HD5; Antigen NY-CO-9

Species Reactivities:Bovine, Porcine, Rat, Mouse, Human

Tag Line:Affinity purified rabbit polyclonal antibody to detect phosphorylation of HDAC5 at Ser498 in human, mouse, rat, bovine and porcine samples

Formulation:In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application:Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting

Positive Control:/

Application And Usages:WB 1:500 - 1:1000, IHC 1:100 - 1:200, IF 1:100 - 1:500

Handling:The antibody solution should be gently mixed before use.