Phospho-CCR5(Ser349) Antibody

Phospho-CCR5(Ser349) Antibodyis available at Gentaur for Next week Delivery.

Description: CCR5 a 7-transmembrane G-linked receptor for a number of inflammatory C-C type chemokines including MIP-1-alpha, MIP-1-beta and RANTES. Transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (along with CD4) for HIV-1 R5 isolates. Interacts with PRAF2. Interacts with HIV-1 surface protein gp120. Efficient ligand binding to CCL3/MIP-1alpha and CCR4/MIP-1beta requires sulfation, Oglycosylation and sialic acid modifications. Glycosylation on S6 is required for efficient binding of CCL4.

Immunogen Sequence:A synthesized peptide derived from human CCR5 around the phosphorylation site of Sersine 349.

Target Alternative Name:AM4 7, C-C chemokine receptor type 5, CC CKR 5, CCR 5, CD 195, Chemokine receptor CCR5, CHEMR13, CKR 5, CMKBR 5, FLJ78003, HIV1 fusion coreceptor, IDDM22, MIP-1 alpha receptor

Species Reactivities:Human

Tag Line:Polyclonal antibody to detect Phospho-CCR5(Ser349)

Formulation:In phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification: Affinity purified

Application:Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blotting, ELISA

Positive Control:/

Application And Usages:WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Handling:The antibody solution should be gently mixed before use.