PGC-1alpha Antibody

PGC-1alpha Antibodyis available at Gentaur for Next week Delivery.

Description: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may also be involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.

Immunogen Sequence:Synthetic peptide surrounding amino acid 766 of mouse PGC-1alpha

Target Alternative Name:peroxisome proliferator-activated receptor gamma coactivator 1-alpha, PPAR Gamma Coactivator-1, Pgc-1alphaa, PPAR gamma coactivator variant form, PGC-1-alpha, PPARGC-1-alpha, PPAR-gamma coactivator 1-alpha

Species Reactivities:Human, mouse, rat

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Formulation:30 µg (0.5 mg/ml) affinity purified rabbit anti-PGC-1alpha polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal

Purification: Affinity purified

Application:Western blot

Positive Control:Jurkat cell lysate

Application And Usages:Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate can be used as a positive control.

Handling:The antibody solution should be gently mixed before use.