p44/42 MAPK (Erk1/2) Antibody

p44/42 MAPK (Erk1/2) Antibodyis available at Gentaur for Next week Delivery.

Description: The extracellular signal-regulated kinase 1 and 2 (Erk1 and Erk2) are closely related mitogen activated protein (MAP) kinases that are activated throμgh the extracellular stimulation by many growth factors, mitogens and differentiation promoting agents via a protein kinase cascade. Erk1/2 are activated approximately 1000 fold by phosphorylation of neighboring threonine and tyrosine residues by Mek1 and Mek2. Both sites must be phosphorylated for maximum activity. Erk1/2 kinases are ubiquitously distributed in the nervous system, as well as a broad range of cells and tissues. These two kinases represent proximal kinases in the classical MAP kinase cascade pathway which links growth and differentiation signals at the cell surface (throμgh tyrosine kinase) with transcription in the nucleus.

Immunogen Sequence:Synthetic peptide surrounding amino acid 340 of rat ERK2/MAPK1

Target Alternative Name:MAPK1, p38, ERK , P42MAPK, ERK2 , p40 , PRKM1 , p41mapk , PRKM2, MAPK2 , p42-MAPK, p41 , ERK-2, ERT1

Species Reactivities:Human, mouse, rat, sheep, chicken

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Formulation:30 µg (0.5 mg/ml) affinity purified rabbit anti- ERK2/MAPK1polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot

Positive Control:Mouses 3T3 cell lysate, Jurkat cell lysate, rat kidney tissue lysate

Application And Usages:Western Blot analysis (1-4 µg/ml).

Handling:The antibody solution should be gently mixed before use.