MBD2a Antibody

MBD2a Antibodyis available at Gentaur for Next week Delivery.

Description: The MBD family of proteins includes MeCP2, MBD1, MBD2, MBD3 and MBD4. MBD2 is highly similar to MBD3 but only MBD2 targets the MeCP1 complex to methylate DNA. MBD2 has two isoforms, MBD2a and MBD2b. MBD2a is a 414 amino acids protein, whereas MBD2b lacks the 152 amino acids N-terminal extension. MBD2a interacts with RNA helicase A to enhance CREB-dependent gene exptression.

Immunogen Sequence:Synthetic peptide surrounding amino acid 164 of rat MBD2a

Target Alternative Name:Methyl-CpG-binding domain protein 2

Species Reactivities:Human, mouse, rat

Tag Line:/

Formulation:30 µg (0.5 mg/ml) affinity purified rabbit anti- MBD2a polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot

Positive Control:Jurkat cell lysate

Application And Usages:The antibody can be used in Western Blot analysis (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Blocking peptide (Cat.# 3232BP-50) is available separately.

Handling:The antibody solution should be gently mixed before use.