LOK Antibody

LOK Antibodyis available at Gentaur for Next week Delivery.

Description: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. LOK (Lymphocyte-oriented kinase), also known as STK10 (serine/threonine kinase 10), is a 968 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Expressed in lymphoid organs, LOK functions to catalyze the ATP-dependent phosphorylation of target proteins, such as MBP (myelin basic protein) and Histone H2A, thereby playing a role in signaling pathways throughout the cell.

Immunogen Sequence:Synthetic peptide derived from human LOK

Target Alternative Name:LOK, Lymphocyte Oriented Kinase, STK10, STK-10, Serine/Threonine Kinase 10

Species Reactivities:Human, mouse

Tag Line:/

Formulation:100 µl affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA and 0.02% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunoprecipitation

Positive Control:/

Application And Usages:Western blotting (1:500 – 1:2000) and Immunoprecipitation. However, the optimal concentrations should be determined individually. The antibody recognizes the LOK of human and mouse origins. Reactivity to other species has not been tested.

Handling:The antibody solution should be gently mixed before use.