Leptin Receptor Antibody

Leptin Receptor Antibodyis available at Gentaur for Next week Delivery.

Description: Leptin is a recently identified protein product of the mouse obese gene. Mice with mutations in the obese gene that block the synthesis of leptin have been found to be obese and diabetic and to have reduced activity, metabolism and body temperature. cDNA clones encoding leptin have been isolated from human, simian, mouse and rat cells. Human leptin shares approximately 84% sequence identity with the mouse protein. Human Leptin cDNA encodes a 167 amino acide residue protein with a 21 amino acid residue signal sequence that is cleaved to yield the 146 amino acid residue mature protein. The expression of leptin mRNA has been shown to be restricted to adipose tissue. Leptin plays an important role in reproduction, immunological response and neuroendocrine signaling.

Immunogen Sequence:Recombinant mouse leptin receptor (a.a. 25-208)

Target Alternative Name:LEP; OB; OBS; Obese Protein

Species Reactivities:Mouse

Tag Line:/

Formulation:100 µg (0.5 mg/ml) affinity purified rabbit anti-mouse Leptin Receptor polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.

Purification: Affinity purified

Application:Western blot

Positive Control:/

Application And Usages:Western blot analysis (0.5-2 µg/ml). However, the optimal conditions should be determined individually.

Handling:The antibody solution should be gently mixed before use.