JNK Antibody

JNK Antibodyis available at Gentaur for Next week Delivery.

Description: The JNK pathway is activated by largely distinct stimuli including inflammatory cytokines (such as TNF-α and IL-1), UV light, inhibitors of protein synthesis and osmotic stress. Activated MEKK1 phosphorylates SEK1 (also known as MKK4), which in turn activates SAPK (also known as JNK). JNK binds tightly to the N-terminal region of c-Jun and ATF-2, and phosphorylates c-Jun at Ser63 and Ser73 and ATF-2 at Thr69 and Thr71.

Immunogen Sequence:Synthetic peptide surrounding amino acid 412 of human JNK-1

Target Alternative Name:JNK1, JNK 1 , JNK1 antibody ,SARP , JNK1A2 , JNK , JAK 1A , JAK1A , Stress activated protein kinase

Species Reactivities:Human, mouse, rat

Tag Line:/

Formulation:30 µg (0.5 mg/ml) affinity purified rabbit anti-JNK polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunoprecipitation, Immunohistochemistry

Positive Control:/

Application And Usages:Western blotting (0.5-4 µg/ml),immunoprecipitation (10-20 µg/ml), and Immunohistochemistry (10-20 µg/ml). Reacts with human and to a lesser extent with mouse and rat. However, the optimal conditions should be determined individually.

Handling:The antibody solution should be gently mixed before use.