Description
JIK Antibodyis available at Gentaur for Next week Delivery.
Description: JNK/SAPK-inhibitory kinase (JIK) is a serine/threonine kinase that belongs to the STE20 kinase family. The kinase domain of JIK is similar to the GCK-like subfamily of STE20 kinases, while its non-catalytic domain is similar to a Caenorhabditis elegans putative serine/threonine kinase, SULU. JIK inhibits c-Jun NH2-terminal kinase/stress-activated protein kinase (JNK/SAPK), which is activated by many types of cellular stresses and extracellular signals. JNK/SAPK regulates cell survival, apoptosis and proliferation in mouse development. JIK is negatively regulated by epidermal growth factor (EGF) and tyrosine kinase receptors. In unstimulated human T cells, JIK is cytoplasmic, whereas in the continuously dividing human T cells of Jurkat lymphoma, JIK is nuclear.
Immunogen Sequence:Synthetic peptide of human JIK/TAOK3
Target Alternative Name:JIK, JNK/SAPK-Inhibitory Kinase, TAOK3, TAO Kinase 3, DPK, Dendritic cell derived protein kinase, MAP3K18
Species Reactivities:Human, mouse
Tag Line:/
Formulation:100 µl affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA and 0.02% thimerosal.
Purification: Affinity purified
Application:Western blot, Immunoprecipitation
Positive Control:/
Application And Usages:Western blotting (1:500 – 1:2500) and Immunoprecipitation. However, the optimal concentrations should be determined individually. The antibody recognizes the JIK/TAOK3 of human and mouse origins. Reactivity to other species has not been tested.
Handling:The antibody solution should be gently mixed before use.
Additional Information
Size: |
100 µl |
Antibody Target: |
JIK |
Category: |
JIK |
Lot Number: |
51084 |
Host: |
Rabbit |
Antibody Type: |
Polyclonal |
Isotype: |
Rabbit IgG |
Accession Number: |
NP_057365.2 |
Gene Id: |
51347 |
Concentration: |
N/A |
Appearance: |
Colorless liquid |
Form: |
Liquid |
Storage Condition: |
-20 °C |
Shipping Condition: |
gel pack |
Shelf Life: |
12 months |
Country of Animal Origin: |
China |
Country of Manufacture: |
USA |
Usage: |
For Research Use Only! Not to be used in humans. |
Western Blot Verified: |
Verified |
Immunocytochemistry Verified: |
Not Verified |
Immunofluorescence Verified: |
Not Verified |
Immunoprecipitation Verified: |
Not Verified |
FACS Verified: |
Not Verified |
ELISA Verified: |
Not Verified |
ChIP Verified: |
Not Verified |
Flow Cytometry Verified: |
Not Verified |